Intragenomic Processor. Epistasis, heterosis and pleiotropy study by DNA real time sequencing using spectroscopy transition method.
Intragenomic Processor.
Epistasis, heterosis and pleiotropy study by DNA real time sequencing using spectroscopy transition method
Study aspects
- Interactions between loci and alleles within the genome
- Locus dependency on the presence of one or more modifier genes
- Outbreeding enhancement
- Gene influences with two or more seemingly unrelated phenotypic traits
The clinical applications
- Gene discovery and diagnosis of rare monogenic disorders
- Identification and diagnosis of genetic factors contributing to common disease
- Pharmacogenetics and targeted therapy
- Prenatal diagnosis and testing
- Infectious diseases
- Personalized medicine
- Gene therapy
- Genome editing
Basic electronic parameters
- Real-Time OS and firmware
- RT resolution 5ns
- Scanning pitch 500 nm
- Pitch resolution 2nm
- Scanning mechanical speed 100mm/s with mechanical acceleration 2500mm/s/2
- RT Processing 250MHz ADC
- Positive Pressure up to 80psi
- Negative Pressure up to -0.5bar
- Peltier temperature variation -5 to +80C
Equipment
- IR and UV Fiber laser
- PDM Custom Spectrometer
- Newport nano step stages and XPS-RL controllers
- PDM Pneumatic Nest
- ThorLabs Optomechanics
- MITUTOYO Optics
- NI PXIe8880 peripheral, RT OS
Conclusion
Intragenomic Processor DNA decoder in our hands can confidently assert the results that will occur in real time during the construction of the genome to turn the research from the field of guesswork and statistics to a real scientific basis.
Below is a links to my work on Intragenomic Processor and some bibliography and references.
Alex Kor, MS